Lysine 419 targets human glucocorticoid receptor for proteasomal degradation

A very straight-forward and classic approach to characterize a new level of GR protein degradation.

Lysine 419 targets human glucocorticoid receptor for proteasomal degradation

Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors

http://www.nature.com/doifinder/10.1038/sj.bjc.6605810

This group developed a very cool gold-nanoparticles sensors array for the detection of cancer by exhalation. The molecular differences of cancer are expressed also in the production of volatile organic compounds that can be detected in the breath. The sensors array can sense those and can also distinguish between the different types of cancers. Overall it looks like something that can be further developed into a very favorable diagnostic tool for its high sensitivity, and the non-invasiveness.

It is also nice that this group is from Israel!